As with any natural health product, you should consult a healthcare practitioner prior to use of this product, especially if you are pregnant, breastfeeding, following a low protein diet, or taking medication for cardiovascular diseases, erectile dysfunction, and/or blood thinners. Consult a healthcare practitioner prior to use if you have a renal/kidney disease or suffer from a cardiovascular disease and are attempting an increase in physical activity. Consult a healthcare practitioner if your cardiovascular condition worsens. Do not use if seal is broken. Keep out of reach of children.